- While the concept seems simple, it required decades of work for mRNA vaccines to overcome a series of hurdles.
- First, scientists learned how to modify mRNA so that it did not produce violent immune system reactions.
- Second, they learned how to encourage immune system cells to gobble up the mRNA as it passed by in the blood.
- Third, they learned how to coax those cells to make large amounts of the critical piece of protein.
- Finally, they learned how to enclose the mRNA inside microscopically small capsules to protect it from being destroyed by chemicals in our blood.
- Already, mRNA vaccines are being tested for other infectious agents, such as Ebola, Zika virus, and influenza. Cancer cells make proteins that also can be targeted by mRNA vaccines: indeed, recent progress was reported with melanoma. And theoretically, mRNA technology could produce proteins missing in certain diseases, like cystic fibrosis.
- mRNA 這種技術一定會在未來徹底改變很多疾病的治療。
mRNA(閱讀鏈接)
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