1. 在Matlab命令窗口輸入命令：
help imwrite
會有如下解釋：
If the input array is of class uint16 and the format supports 16-bit data (JPEG, PNG, and TIFF), imwrite outputs the data as 16-bit values. If the format does not support 16-bit values, imwrite issues an error. Several formats, such as JPEG and PNG, support a parameter that lets you specify the bitdepth of the output data.
If the input array is of class double, and the image is a grayscale or RGB color image, imwrite assumes the dynamic range is [0,1] and automatically scales the data by 255 before writing it to the file as 8-bit values.
2. 如果你要保存成uint16的灰度圖像的矩陣數據是非uint16的類型：
則必須先將double類型轉換爲uint16的類型，執行命令：
data11=uint16(data1);
結果如下：
3. 然後執行命令：
imwrite(data11,'image.png','png','bitdepth',16);
最終得到uint16的灰度圖像image.png。如下圖所示：
參考網址：https://wenda.so.com/q/1534806305217644