Metastasis suppressor genes
| Metastasis suppressor | Mechanism of action |
|---|---|
| AKAP12 | PKA regulation |
| BRMS1 | Transcription regulation |
| Caspase 8 | Apoptosis |
| CDH1 | Cell adhesion |
| CDH11 | Cell adhesion |
| CD44 | Hyaluronic acid receptor |
| CRSP3 | Transcription regulation |
| DCC | Cell adhesion |
| DLC1 | Rho-GTPase activation |
| DRG1 | Angiogenesis |
| GAS1 | Apoptosis |
| Gelsolin | Actin depolymerization |
| KAI1 | Apoptosis |
| KISS1/KISS1R | Tumor dormancy maintenance |
| KLF17 | Transcription regulation |
| LSD1 | Chromotin remodeling |
| MAP2K4 | MAPKK signaling |
| MKK4 | MAPK signaling |
| MAK7 | MAPK signaling |
| MicroRNA-335, 126 | Suppression of SOX4, MERTK, PTPRN2, TNC |
| Nm23 | MAPK signaling |
| PEBP1 | Raf kinase inhibition |
| RhoGDI2 | Rho signaling |
| RRM1 | PTEN upregulation |
| TXNIP | Redox regulation |
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